It’s 1999 San Francisco and 20-something visual artist Sarah is partying accordingly. Recently promoted from answering the phones to illustrating the covers at the queer indie magazine where she works, and in a new, (potentially serious?) relationship with motorcycle-riding goddess Donimo, life is good. But when Sarah flies back east to visit her family, something feels off with her mom, Midge, and a visit to a neurologist soon upends their world as they know it.

When Heterosis - a mysterious virus that turns gay men straight sweeps through the Parisian gay scene, Jim, the six packed sovereign of the Gym Queens, goes from Pride royalty to social outcast. With only Lucien, a freshly-out twink with more heart than abs, still by his side, Jim must race to find a cure before the disease erases the community that once worshipped him.

Introverted lesbian space princess Saira embarks on a mission to rescue her ex from evil incel aliens, enlisting the help of an enby popstar and a cantankerous boomer spaceship.